/* ============================================================
   Model Organism — editorial stylesheet
   Preclinical peptide research, explained.
   Mobile-first. No frameworks. No build step.
   ============================================================ */

:root {
  --ink:    #16191C;
  --paper:  #F7F5F1;
  --rule:   #DFDBD3;
  --slate:  #5C6469;
  --signal: #2F5D62;

  --serif: "Instrument Serif", Georgia, "Times New Roman", serif;
  --sans:  "Public Sans", -apple-system, "Segoe UI", Helvetica, Arial, sans-serif;
  --mono:  "JetBrains Mono", "SF Mono", Consolas, "Liberation Mono", monospace;

  --measure: 72ch;
  --wide: 1180px;
}

/* ---------- Reset & base ---------- */

*,
*::before,
*::after {
  box-sizing: border-box;
  margin: 0;
  padding: 0;
}

html {
  -webkit-text-size-adjust: 100%;
}

body {
  background: var(--paper);
  color: var(--ink);
  font-family: var(--sans);
  font-size: 1.0625rem;
  font-weight: 400;
  line-height: 1.7;
}

img {
  max-width: 100%;
  height: auto;
  display: block;
}

a {
  color: var(--signal);
  text-decoration: underline;
  text-decoration-thickness: 1px;
  text-underline-offset: 3px;
}

a:hover {
  color: var(--ink);
}

a:focus-visible,
button:focus-visible,
input:focus-visible {
  outline: 2px solid var(--signal);
  outline-offset: 3px;
}

::selection {
  background: var(--signal);
  color: var(--paper);
}

/* ---------- Type ---------- */

h1, h2, h3 {
  font-family: var(--serif);
  font-weight: 400;
  line-height: 1.15;
  letter-spacing: 0.005em;
}

h1 { font-size: clamp(2.4rem, 6vw, 4rem); }
h2 { font-size: clamp(1.7rem, 4vw, 2.4rem); }
h3 { font-size: clamp(1.25rem, 2.5vw, 1.5rem); }

h4 {
  font-family: var(--sans);
  font-size: 0.8125rem;
  font-weight: 600;
  letter-spacing: 0.14em;
  text-transform: uppercase;
  color: var(--slate);
}

.kicker {
  font-family: var(--mono);
  font-size: 0.75rem;
  font-weight: 500;
  letter-spacing: 0.18em;
  text-transform: uppercase;
  font-variant: small-caps;
  color: var(--signal);
  display: block;
  margin-bottom: 0.9rem;
}

.prose {
  max-width: var(--measure);
}

.prose p + p {
  margin-top: 1.1em;
}

.muted {
  color: var(--slate);
}

.small {
  font-size: 0.9rem;
}

/* ---------- Layout primitives ---------- */

.wrap {
  width: 100%;
  max-width: var(--wide);
  margin-inline: auto;
  padding-inline: 1.25rem;
}

.section {
  padding-block: 3.5rem;
}

.rule {
  border: 0;
  border-top: 1px solid var(--rule);
}

.rule--short {
  width: 4.5rem;
  margin: 1.6rem 0;
  border-top: 1px solid var(--ink);
}

/* ---------- Skip link ---------- */

.skip-link {
  position: absolute;
  left: -9999px;
  top: 0;
  background: var(--ink);
  color: var(--paper);
  padding: 0.6rem 1.1rem;
  font-family: var(--mono);
  font-size: 0.8rem;
  z-index: 100;
}

.skip-link:focus {
  left: 0.5rem;
  top: 0.5rem;
}

/* ---------- Header & nav ---------- */

.site-header {
  border-bottom: 1px solid var(--rule);
  background: var(--paper);
}

.site-header .wrap {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  justify-content: space-between;
  gap: 0.75rem 1.5rem;
  padding-block: 1.1rem;
}

.logo {
  display: inline-flex;
  align-items: center;
  gap: 0.7rem;
  text-decoration: none;
  color: var(--ink);
}

.logo:hover {
  color: var(--signal);
}

.logo-mark {
  width: 30px;
  height: 30px;
  flex: none;
  color: currentColor;
}

.logo-word {
  font-family: var(--serif);
  font-size: 1.25rem;
  letter-spacing: 0.16em;
  white-space: nowrap;
}

.site-nav ul {
  list-style: none;
  display: flex;
  gap: 1.4rem;
}

.site-nav a {
  font-family: var(--sans);
  font-size: 0.875rem;
  font-weight: 500;
  letter-spacing: 0.06em;
  text-transform: uppercase;
  text-decoration: none;
  color: var(--slate);
  padding-block: 0.35rem;
  border-bottom: 2px solid transparent;
}

.site-nav a:hover {
  color: var(--ink);
}

.site-nav a.is-current {
  color: var(--ink);
  border-bottom-color: var(--signal);
}

/* ---------- Standing note bar ---------- */

.note-bar {
  border-bottom: 1px solid var(--rule);
  background: color-mix(in srgb, var(--paper) 92%, var(--signal) 8%);
}

.note-bar p {
  font-family: var(--mono);
  font-size: 0.75rem;
  line-height: 1.6;
  color: var(--slate);
  padding-block: 0.65rem;
}

/* ---------- Hero ---------- */

.hero {
  padding-block: 4.5rem 3.5rem;
  border-bottom: 1px solid var(--rule);
}

.hero .tagline {
  font-family: var(--serif);
  font-style: italic;
  font-size: clamp(1.25rem, 3vw, 1.65rem);
  color: var(--slate);
  margin-top: 0.8rem;
}

.hero .positioning {
  max-width: var(--measure);
  margin-top: 1.4rem;
  font-size: 1.1rem;
}

.hero .kicker {
  margin: 1.6rem 0 0;
}

.cta {
  display: inline-block;
  margin-top: 2rem;
  font-family: var(--sans);
  font-weight: 600;
  font-size: 0.95rem;
  letter-spacing: 0.04em;
  color: var(--paper);
  background: var(--ink);
  padding: 0.85rem 1.6rem;
  text-decoration: none;
  border: 1px solid var(--ink);
  transition: background 0.15s ease, color 0.15s ease;
}

.cta:hover {
  background: var(--paper);
  color: var(--ink);
}

/* ---------- Teasers ---------- */

.teasers {
  display: grid;
  gap: 2.5rem;
  margin-top: 2.5rem;
}

.teaser {
  border-top: 1px solid var(--ink);
  padding-top: 1.2rem;
}

.teaser img,
.teaser .img-fallback {
  aspect-ratio: 3 / 2;
  object-fit: cover;
  width: 100%;
  margin-bottom: 1.1rem;
  filter: saturate(0.85);
}

.tag {
  font-family: var(--mono);
  font-size: 0.7rem;
  font-weight: 500;
  letter-spacing: 0.16em;
  text-transform: uppercase;
  color: var(--signal);
}

.teaser h3 {
  margin-top: 0.55rem;
}

.teaser h3 a {
  color: var(--ink);
  text-decoration: none;
}

.teaser h3 a:hover {
  color: var(--signal);
  text-decoration: underline;
}

.teaser .excerpt {
  margin-top: 0.6rem;
  color: var(--slate);
  font-size: 0.95rem;
}

.byline {
  font-family: var(--mono);
  font-size: 0.72rem;
  color: var(--slate);
  margin-top: 0.9rem;
  letter-spacing: 0.04em;
}

/* ---------- Pull quote ---------- */

.pullquote {
  border-top: 1px solid var(--ink);
  border-bottom: 1px solid var(--ink);
  padding: 3rem 0;
  margin-block: 3.5rem;
  max-width: 56rem;
}

.pullquote blockquote {
  border: 0;
  margin: 0;
  padding: 0;
}

.pullquote blockquote p {
  font-family: var(--serif);
  font-size: clamp(1.6rem, 4vw, 2.3rem);
  line-height: 1.3;
  font-style: italic;
}

.pullquote cite {
  display: block;
  margin-top: 1.4rem;
  font-family: var(--mono);
  font-style: normal;
  font-size: 0.75rem;
  letter-spacing: 0.14em;
  text-transform: uppercase;
  color: var(--slate);
}

/* ---------- Method cards ---------- */

.method-cards {
  display: grid;
  gap: 1.5rem;
  margin-top: 2.2rem;
}

.method-card {
  border: 1px solid var(--rule);
  border-top: 1px solid var(--ink);
  padding: 1.4rem 1.4rem 1.6rem;
}

.method-card .num {
  font-family: var(--mono);
  font-size: 0.72rem;
  color: var(--signal);
  letter-spacing: 0.14em;
}

.method-card h3 {
  font-size: 1.25rem;
  margin-top: 0.5rem;
}

.method-card p {
  margin-top: 0.65rem;
  font-size: 0.92rem;
  color: var(--slate);
}

/* ---------- Newsletter ---------- */

.newsletter {
  border: 1px solid var(--rule);
  border-top: 1px solid var(--ink);
  padding: 2.2rem 1.6rem;
  max-width: 44rem;
}

.newsletter h2 {
  font-size: 1.6rem;
}

.newsletter p {
  margin-top: 0.5rem;
  color: var(--slate);
  font-size: 0.95rem;
}

.field-row {
  display: flex;
  flex-wrap: wrap;
  gap: 0.7rem;
  margin-top: 1.3rem;
}

.field-row label {
  flex-basis: 100%;
  font-family: var(--mono);
  font-size: 0.72rem;
  letter-spacing: 0.14em;
  text-transform: uppercase;
  color: var(--slate);
}

input[type="email"] {
  flex: 1 1 14rem;
  font-family: var(--sans);
  font-size: 0.95rem;
  padding: 0.7rem 0.9rem;
  border: 1px solid var(--slate);
  background: var(--paper);
  color: var(--ink);
  border-radius: 0;
}

input[type="email"]::placeholder {
  color: var(--slate);
}

button[type="submit"] {
  font-family: var(--sans);
  font-weight: 600;
  font-size: 0.85rem;
  letter-spacing: 0.06em;
  text-transform: uppercase;
  color: var(--paper);
  background: var(--ink);
  border: 1px solid var(--ink);
  padding: 0.7rem 1.5rem;
  cursor: pointer;
  border-radius: 0;
  transition: background 0.15s ease, color 0.15s ease;
}

button[type="submit"]:hover {
  background: var(--signal);
  border-color: var(--signal);
}

/* ---------- Research library ---------- */

.page-head {
  padding-block: 3.5rem 2.5rem;
  border-bottom: 1px solid var(--rule);
}

.page-head .lede {
  max-width: var(--measure);
  margin-top: 1.2rem;
  font-size: 1.12rem;
}

.standing-note {
  border: 1px solid var(--rule);
  border-left: 3px solid var(--signal);
  padding: 1rem 1.2rem;
  margin-top: 1.8rem;
  max-width: var(--measure);
  font-size: 0.9rem;
  color: var(--slate);
}

.category-rail {
  display: flex;
  flex-wrap: wrap;
  gap: 0.6rem;
  margin-top: 2rem;
}

.category-rail span {
  font-family: var(--mono);
  font-size: 0.72rem;
  letter-spacing: 0.12em;
  text-transform: uppercase;
  color: var(--slate);
  border: 1px solid var(--rule);
  padding: 0.35rem 0.8rem;
}

.category-rail span:first-child {
  color: var(--paper);
  background: var(--ink);
  border-color: var(--ink);
}

.profile {
  padding-block: 3.5rem;
  border-bottom: 1px solid var(--rule);
  scroll-margin-top: 2rem;
}

.profile .label {
  font-family: var(--mono);
  font-size: 0.72rem;
  letter-spacing: 0.14em;
  text-transform: uppercase;
  color: var(--signal);
}

.profile h2 {
  margin-top: 0.7rem;
}

.profile .subhead {
  font-family: var(--serif);
  font-style: italic;
  font-size: 1.2rem;
  color: var(--slate);
  margin-top: 0.5rem;
}

.profile h3 {
  font-family: var(--sans);
  font-size: 0.8rem;
  font-weight: 600;
  letter-spacing: 0.14em;
  text-transform: uppercase;
  color: var(--ink);
  margin-top: 2rem;
}

.profile h3 + p {
  margin-top: 0.7rem;
}

.profile .prose {
  max-width: var(--measure);
}

.snapshot {
  font-family: var(--mono);
  font-size: 0.8rem;
  line-height: 1.75;
  border: 1px solid var(--rule);
  border-left: 3px solid var(--signal);
  padding: 1.3rem 1.4rem;
  margin-top: 2.2rem;
  max-width: 40rem;
  color: var(--ink);
}

.snapshot dt {
  color: var(--slate);
  letter-spacing: 0.1em;
  text-transform: uppercase;
  font-size: 0.68rem;
  margin-top: 0.7rem;
}

.snapshot dt:first-child {
  margin-top: 0;
}

.snapshot dd {
  margin: 0;
}

.figure {
  margin-block: 3rem;
}

.figure img {
  width: 100%;
  aspect-ratio: 16 / 9;
  object-fit: cover;
  filter: saturate(0.85);
}

.figure figcaption {
  font-family: var(--mono);
  font-size: 0.72rem;
  color: var(--slate);
  margin-top: 0.7rem;
  letter-spacing: 0.04em;
}

/* ---------- About ---------- */

.mission {
  border: 1px solid var(--ink);
  padding: 2.2rem 2rem;
  margin-block: 3rem;
  max-width: 46rem;
}

.mission p {
  font-family: var(--serif);
  font-size: 1.45rem;
  line-height: 1.45;
}

.standards-list {
  list-style: none;
  margin-top: 1.6rem;
  max-width: var(--measure);
  counter-reset: std;
}

.standards-list li {
  border-top: 1px solid var(--rule);
  padding: 1.1rem 0 1.1rem 2.4rem;
  position: relative;
}

.standards-list li::before {
  content: counter(std, decimal-leading-zero);
  counter-increment: std;
  position: absolute;
  left: 0;
  top: 1.2rem;
  font-family: var(--mono);
  font-size: 0.75rem;
  color: var(--signal);
}

.standards-list strong {
  font-weight: 600;
}

.team-grid {
  display: grid;
  gap: 2.5rem;
  margin-top: 2.5rem;
}

.team-card img,
.team-card .img-fallback {
  aspect-ratio: 1 / 1;
  object-fit: cover;
  width: 100%;
  max-width: 260px;
  filter: grayscale(0.35) saturate(0.8);
}

.team-card h3 {
  margin-top: 1.1rem;
}

.team-card .role {
  font-family: var(--mono);
  font-size: 0.72rem;
  letter-spacing: 0.14em;
  text-transform: uppercase;
  color: var(--signal);
  margin-top: 0.25rem;
}

.team-card p {
  margin-top: 0.7rem;
  font-size: 0.93rem;
  color: var(--slate);
}

.corrections {
  border: 1px solid var(--rule);
  border-left: 3px solid var(--signal);
  padding: 1.5rem 1.6rem;
  max-width: var(--measure);
  margin-top: 3rem;
}

/* ---------- Privacy / legal ---------- */

.legal .prose h2 {
  font-size: 1.55rem;
  margin-top: 2.8rem;
}

.legal .prose h3 {
  font-family: var(--sans);
  font-size: 0.85rem;
  font-weight: 600;
  letter-spacing: 0.12em;
  text-transform: uppercase;
  margin-top: 2rem;
}

.legal .prose h2 + p,
.legal .prose h3 + p {
  margin-top: 0.8rem;
}

.legal .prose ul {
  margin: 0.8rem 0 0 1.2rem;
}

.legal .prose li + li {
  margin-top: 0.4rem;
}

.updated {
  font-family: var(--mono);
  font-size: 0.75rem;
  letter-spacing: 0.1em;
  color: var(--slate);
  text-transform: uppercase;
}

.terms-block {
  border-top: 1px solid var(--ink);
  margin-top: 3.5rem;
  padding-top: 1rem;
}

/* ---------- Footer ---------- */

.site-footer {
  border-top: 1px solid var(--ink);
  margin-top: 4rem;
  padding-block: 3rem 2rem;
  background: var(--paper);
}

.footer-top {
  display: grid;
  gap: 2.5rem;
}

.footer-brand .tagline {
  font-family: var(--serif);
  font-style: italic;
  color: var(--slate);
  margin-top: 0.7rem;
  font-size: 1.05rem;
}

.footer-cols {
  display: grid;
  gap: 2rem;
}

.footer-col h2 {
  font-family: var(--mono);
  font-size: 0.72rem;
  font-weight: 500;
  letter-spacing: 0.16em;
  text-transform: uppercase;
  color: var(--slate);
}

.footer-col ul {
  list-style: none;
  margin-top: 0.9rem;
}

.footer-col li {
  margin-top: 0.45rem;
  font-size: 0.92rem;
}

.footer-col a {
  color: var(--ink);
  text-decoration: none;
}

.footer-col a:hover {
  color: var(--signal);
  text-decoration: underline;
}

.footer-col address {
  font-style: normal;
  font-size: 0.92rem;
  line-height: 1.6;
}

.footer-news {
  border-top: 1px solid var(--rule);
  margin-top: 2.5rem;
  padding-top: 2rem;
  max-width: 34rem;
}

.footer-news h2 {
  font-family: var(--serif);
  font-size: 1.3rem;
  font-weight: 400;
}

.social-row {
  display: flex;
  gap: 1rem;
  margin-top: 2rem;
}

.social-row a {
  color: var(--slate);
  display: inline-flex;
  padding: 0.3rem;
}

.social-row a:hover {
  color: var(--signal);
}

.social-row svg {
  width: 20px;
  height: 20px;
}

.footer-disclaimer {
  border-top: 1px solid var(--rule);
  margin-top: 2.5rem;
  padding-top: 1.6rem;
  font-size: 0.82rem;
  color: var(--slate);
  max-width: var(--measure);
}

.footer-legalline {
  margin-top: 1.6rem;
  font-family: var(--mono);
  font-size: 0.72rem;
  color: var(--slate);
  letter-spacing: 0.04em;
}

/* ---------- WordPress admin bar offset ---------- */

body.admin-bar .skip-link:focus {
  top: 42px;
}

/* ---------- Breakpoints ---------- */

@media (min-width: 640px) {
  .wrap { padding-inline: 2rem; }
  .method-cards { grid-template-columns: 1fr 1fr; }
  .footer-cols { grid-template-columns: repeat(3, 1fr); }
  .team-grid { grid-template-columns: repeat(2, 1fr); }
}

@media (min-width: 900px) {
  .section { padding-block: 4.5rem; }
  .teasers { grid-template-columns: repeat(3, 1fr); gap: 2rem; }
  .method-cards { grid-template-columns: repeat(4, 1fr); }
  .team-grid { grid-template-columns: repeat(3, 1fr); }
  .footer-top { grid-template-columns: 1.2fr 2fr; align-items: start; }
  .hero { padding-block: 6rem 4.5rem; }
}

@media (min-width: 1180px) {
  .wrap { padding-inline: 2.5rem; }
}

/* ---------- Motion ---------- */

html {
  scroll-behavior: smooth;
}

@media (prefers-reduced-motion: reduce) {
  *,
  *::before,
  *::after {
    transition: none !important;
    animation: none !important;
  }
  html { scroll-behavior: auto; }
}